These pathways include pathways in cancer, p53 signaling pathway, neurotrophin signaling pathway, MAPK signaling pathway, ErbB signaling pathway, mTOR signaling pathway, focal adhesion, endometrial cancer, TGF-β signaling pathway, Ras Pathway, Wnt signaling pathway, PI3K pathway, PDGF signaling pathway, GnRH signaling pathway, adherens junction, gap junction, axon guidance and others (Figure 4B(Fig. 4)). The gene discussed is GNRH1; the disease is cancer.