The mean plasma concentrations of TNF-α were 47.62 ± 2.83 pg/ml for the control group, 46.80 ± 3.26 pg/ml for DF, and 50.07 ± 4.63 pg/ml for DHF patients (P < 0.05; Figure 1(d)). This evidence concerns the gene TNF and Dengue hemorrhagic fever.