What is worth emphasizing is that the assessment of MMP-2 levels did not show the difference between stages 1 and 2 as well stages 2 and 3 of liver fibrosis, highlighting the importance of labeling M30 CK-18 as a more sensitive marker than MMP-2 in predicting liver fibrosis [14]. The gene discussed is KRT18; the disease is Hepatic fibrosis.