When we focused on the patients with newly diagnosed multiple myeloma (n = 8 for no-CIPN and 11 for CIPN), the NGF levels were significantly decreased in the CIPN group (Fig 2B; △NGF = +2.52 ± 8.39 pg/ml for No-CIPN and −4.14 ± 4.87 pg/ml for CIPN; p-value = 0.043). The gene discussed is NGF; the disease is AL amyloidosis.