IL4R and infection: As impaired viability of S. mansoni-infected mice following IL-4Rα knockdown at 6 weeks post-infection (Tam6) was observed (Fig 3B), the associated immune and histopathological responses of Tam6-fed RosaCreERT2-/+IL-4Rα-/lox mice (termed iCre-/+IL-4Rα-/lox Tam6, Fig 5A) was investigated.