IL6 and disease arising from reactivation of latent virus: An association was observed at IL6 rs1818879 (Fig 1), indicating that subjects with latent infections carrying the A allele had a lower risk of progressing to active HAT (p = 0.0001, OR = 0.39, CI95 = [0.24–0.63], BONF = 0.0034) (Table 3).