CFL1 and cancer: IHC grade of cofilin was significantly higher in NPC cancer nests (7.759 ± 3.191) than NNE tissues (2.233 ± 0.753, P = 0.001), Staple diagrams in panel C show a summary of IHC grade value for the tissue samples evaluated, based on the scoring of IHC peroxidase staining in an average of 5 fields/tissue section (Fig. 6).