Similarly, miR-7641 inhibition in MDA-MB-231 breast cancer cells upregulated RPS16, TNFSF10, MSRB3, CDNF, ZNF616, and NBEA, downregulated CUL3, and showed no remarkable changes for PIGC and the other genes (Fig. 4b and Supplementary Fig. S4b). This evidence concerns the gene CUL3 and breast cancer.