In addition, NCL has been found associated with DGCR8 and Drosha, the core components of the microprocessor complex and to be involved in the biogenesis of microRNA 15a/16 (miR-15a/16)23, miR-21, miR-221, miR-222, and miR-103, that are involved in breast cancer initiation, progression, and drug resistance24. This evidence concerns the gene NUCLEOLIN and breast carcinoma.