IGHE and urticaria: Accordingly, it has been demonstrated that OmAb is also effective in several types of inducible urticaria, as solar urticaria34, 35, cold- and heat-induced urticaria36–38 and delayed pressure urticaria or symptomatic dermographism39, 40 where non-IgE-mechanisms have been demonstrated, indicating that OmAb may act beyond IgE-mediated mechanisms.