Next, we analyzed the phosphorylation and intracellular localization of YAP1. Co-incubation of HEYA8 and OVCAR8 ovarian cancer cells with platelets robustly reduced YAP1S127 and YAP1S397 phosphorylation, whereas total YAP1 levels did not change (Fig. 3a, b). The gene discussed is YAP1; the disease is ovarian cancer.