Analyzing TCGA data from high-grade serous ovarian cancer (Supplementary Fig. 2e) indicated that expression of YAP1 or components of the Hippo signaling pathways is mainly regulated by gene amplification and/or mRNA up/downregulation, whereas mutations in these genes are rare, which is consistent with other tumor types22. Here, YAP1 is linked to ovarian serous adenocarcinoma.