Moreover, marked obvious positive CK7 expression were found in patients aged over 60 years old, with smoking history, at T3–4 stages and with lymph node metastasis, invasion, clinical stage, and tumor size over 3 cm compared with patients aged less than 60 years, without smoking history, at T1–2 stages, without lymph node metastasis and invasion, and tumor size less than 3 cm. Here, KRT7 is linked to neoplasm.