Circulating PCSK9 has also been found to be significantly associated with hepatic expression of SREBP‐1c and FASN, whereas PCSK9 mRNA levels have been found to be significantly correlated with steatosis severity and hepatic APOB, SREBP‐1c, and FASN expression (Ruscica et al, 2016). The gene discussed is SREBF1; the disease is steatosis.