Glutamine dependence has been linked to various oncogenes including MYC (Gao et al., 2009; Wise et al., 2008), RAS (Son et al., 2013), IDH (Matre et al., 2014; Seltzer et al., 2010) and hormone receptor status in breast cancers (Gross et al., 2014). This evidence concerns the gene NR4A1 and breast carcinoma.