PGAM5 and cryopyrin-associated periodic syndrome: Expression of PGAM5 was significantly higher in CaP than in benign prostate (score of 2.24 vs 1.58, p=0.00059, t-test) and was higher also in CaPs of Gleason scores 7–10 than in CaP of Gleason score 6 (p<0.05, t-test) (Figure 5A,B).