EGFR and lung cancer: It has been suggested that specific miRNA could act as a molecular diagnostic tool for lung cancer,29, 30 and miRNA-based therapy could potentially be a rational approach for the therapeutic targeting of EGFR.31 Recently, a number of miRNAs such as miR-200a,32 miR-27a/27b,33, 34 miR-133a,35 miR-134,36 miR-143,37 miR-14538 and miR-146a39 have been demonstrated to target EGFR directly.