However, when all groups were analyzed together, prolidase activity was lower at the acute time points (T0, T6) compared with the quiescent state (Tf/u) (RM-ANOVA time point p < 0.0001), and there was marginal evidence that this relationship was modified by the presence or absence of acute MI (p = 0.10) (Figure 2). Here, PEPD is linked to myocardial infarction.