S100A8 and gastritis: It has been reported that a trivalent vaccine including CagA, VacA, and NAP could reduce H. pylori colonization and gastritis in H. pylori-infected Beagle dogs by intramuscular injection with aluminum hydroxide adjuvant, which may be due to antibody responses against CagA, VacA, and NAP (Rossi et al., 2004).