The lower incidence rate of severe hypoglycemia in type 1 diabetes that has now been observed may be a consequence of more intensive diabetes education in Tayside since 1998 [18] along with the greater use of glucose monitoring and insulin pumps, and the introduction of newer insulin analogues, which are associated with a lower rate of hypoglycemia [19], particularly at night. The gene discussed is INS; the disease is type 1 diabetes mellitus.