IL15 and acute myeloid leukemia: In this study, we aimed to assess (i) whether IL-15 induces and expansion of NK cells from healthy donors (HDs) and AML patients and its effect on the expression of activating receptors after short-term culture in vitro; (ii) whether IL-15 increases the cytotoxic activity of NK cells; and (iii) whether the maturation of immature DCs (iDCs) is enhanced by culture with IL-15-stimulated PBMCs.