ADIPOQ and common variable immunodeficiency: Furthermore, cross-reactivity between Acrp30 antibodies and Ig was excluded by testing two different concentrations of Ig (6 and 8 mg/ml) in ELISA, whereas the level of Acrp30 was significantly lower in controls than in CVID patients (17 ± 0.4 versus 27 ± 0.7 μg/ml; p < 0.0001) (Figure 1A).