Bari et al. investigated secretion of soluble CD163 (sCD163), and pro-inflammatory IL-6 and TNFα in gestational diabetes using explants of placenta and adipose tissue from pregnant women and found increased secretion of sCD163 and IL-6 from placenta and adipose tissue explants in GDM (58), pointing toward similarities between HBCs and ATMs. Here, IL6 is linked to gestational diabetes.