A more recent study reported that GnRH receptor expression was detected in 67% of hyperplasia cases (4 out of 6), in 100%of benign fibroadenoma cases (3 out of 3), in 100% of carcinoma in situ cases (4 out of 4), and in 71% cases of malignant breast cancers (22 out of 31) (20). The gene discussed is GNRHR; the disease is cancer.