A malfunctioning T and B cell regulation causing reactions against autoantigens is involved in both conditions with antibody production in rheumatoid arthritis (rheumatoid factor and anti-cyclic citrullinated peptide) and thyroid autoimmunity (thyroid peroxidase, thyroglobulin, and thyroid stimulating hormone receptor antibodies) (1). Here, TSHR is linked to autoimmune thyroid disease.