As shown in Table 1, HOXC10 mRNA expression was significantly associated with smoking status (p = 0.0031), TNM stage (p < 0.0001), lymph node metastasis (p < 0.0001, Figure 1D) and distal metastasis (p < 0.0001, Figure 1E) in lung cancer. The gene discussed is HOXC10; the disease is metastatic malignant neoplasm in the lymph nodes.