Previous studies have demonstrated that cancer metastasis are partially dependent on the ability of tumor cells to adhere to the proteins of the extracellular matrix (ECM) and survive at the distant location (Glinsky and Glinsky, 1996; DeRoock et al., 2001), we thus examined the effects of HOXC10 on tumor cell adhesion to the ECM supportive substrate fibronectin using pre-coated plates (Mahauad-Fernandez et al., 2014). The gene discussed is FN1; the disease is cancer.