These DRG lesions are similar to those described in the P0-CreC;Nf2flox/flox25 and mGFAP-Cre;Nf2flox/flox mice, and are reminiscent of the schwannoma tumorlets found in NF2 patients60, thus demonstrating the necessary role of Nf2 loss for schwannoma formation. The gene discussed is NF2; the disease is schwannoma.