The mGFAP-Cre;Smarcb1flox/flox;Nf2flox/flox mouse model demonstrates that biallelic loss of Smarcb1 loss is dispensable and Nf2 loss is necessary for schwannoma development41, as in mGFAP-Cre;Nf2flox/flox mice. The gene discussed is SMARCB1; the disease is schwannoma.