UGRP1 and UGRP2 have certain similarities between their amino sequences, especially within the antiflammin domain, which is responsible for the anti-inflammatory and immunomodulatory activities of UGRP2, which possesses anti-inflammatory functions.27, 28 Recent studies have demonstrated that UGRP1 is strongly associated with asthma and allergic airway inflammation (http://omim.org/entry/606531).29, 30 Therefore, considering the current literature, we suggest that UGRP2 may also be associated with the pathogenesis of AH and its related phenotypes, such as asthma and allergies. The gene discussed is SCGB3A2; the disease is asthma.