SCGB3A2 and allergic disease: UGRP1 and UGRP2 have certain similarities between their amino sequences, especially within the antiflammin domain, which is responsible for the anti-inflammatory and immunomodulatory activities of UGRP2, which possesses anti-inflammatory functions.27, 28 Recent studies have demonstrated that UGRP1 is strongly associated with asthma and allergic airway inflammation (http://omim.org/entry/606531).29, 30 Therefore, considering the current literature, we suggest that UGRP2 may also be associated with the pathogenesis of AH and its related phenotypes, such as asthma and allergies.