The study by Demontis et al. [51] revealed significant effects of the interactions between two SNPs in the glutamate ionotropic receptor NMDA type subunit 2B (GRIN2B) gene (rs1805539 and rs1806205) and maternal herpes simplex virus type 2 (HSV-2) seropositivity on schizophrenia risk. This evidence concerns the gene GRIN2B and schizophrenia.