In consistent with our findings, Zhang et al. [33] also show that the inhibition of XIAP can reinforce radiation sensitivity and heighten therapeutic outcome of EC treatment, wherein EC cells transfected with XIAP-siRNA presents lower XIAP expressions by activating caspase-3 to increase apoptosis, so it could sensitize cancer cells to chemotherapeutics contributing to a better clinical response. Here, CASP3 is linked to cancer.