Serum concentration of AHA IgM/IgG antibodies was significantly higher in the group with uveitis (mean 19.2 U/ml) than in children without uveitis (mean 10.2 U/ml) in the Swedish and Danish cohort with available sera for antihistone analyses (p = 0.002; chi-square, data not shown). The gene discussed is CD40LG; the disease is uveitis.