COASY and neurodegeneration with brain iron accumulation: Up to now, the genetic basis of 10 types of NBIA has been established which include Aceruloplasminemia [5], Beta-propeller protein-associated neurodegeneration [6], COASY protein-associated neurodegeneration [7, 8], Fatty acid hydroxylase-associated neurodegeneration [9], Kufor-Rakeb syndrome [10], mitochondrial membrane protein-associated neurodegeneration [11], Neuroferritinopathy [12, 13], PLA2G6-associated neurodegeneration (PLAN) [14, 15], Pantothenate kinase-associated neurodegeneration (PKAN) [16], and Woodhouse-Sakati syndrome [17].