The first consists of genes that were differentially expressed in TN-T1D compared to Tempus controls (Set 1: FASLG, FCRL6, GZMB, KLRD1, IGFBP3 and ZNF680) and the second consists of genes that were differentially expressed in RNA samples extracted using the PAXgene vs. Tempus systems (Set 2: COX6C, COX7B, COMMD6, LSM3, RPS24, SUB1, KIF20B, and KIAA1681). The gene discussed is COX6C; the disease is type 1 diabetes mellitus.