By using Scopus database, 53 publications were found following these search criteria: TITLE-ABS-KEY (“omega 3” OR “PUFA” OR “eicosapentaenoic” OR “docosahexaenoic” OR “marine fatty acids” OR “marine lipid” OR “marine oil” OR “fish oil” OR “fish lipid” ) AND TITLE-ABS-KEY (nutrition OR diet) AND TITLE-ABS-KEY (“metabolic disorder” OR “metabolic alteration” OR “metabolic disease” OR obesity OR “metabolic syndrome” OR diabetes OR “cardiovascular disease” OR cholesterol OR insulin OR atherosclerosis OR inflammation OR “oxidative stress”) AND TITLE-ABS-KEY (lipidomic OR lipidomics OR lipidome). This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.