By using Scopus database, 53 publications have been found following the search criteria: TITLE-ABS-KEY (“omega 3” OR “PUFA” OR “eicosapentaenoic” OR “docosahexaenoic” OR “marine fatty acids” OR “marine lipid” OR “marine oil” OR “fish oil” OR “fish lipid”) AND TITE-ABS-KEY (nutrition OR diet) AND TITLE-ABS-KEY (“metabolic disorder” OR “metabolic alteration” OR “metabolic disease” OR obesity OR “metabolic syndrome” OR diabetes OR “cardiovascular disease” OR cholesterol OR insulin OR atherosclerosis OR inflammation OR “oxidative stress”) AND TITE-ABS-KEY (proteomic OR proteomics OR proteome). The gene discussed is INS; the disease is Other metabolic disease.