OGG1 and lung adenocarcinoma: Interestingly, significant increase of lung adenocarcinoma incidence and multiplicity was found in DMBDD-administered Ogg1−/− male mice (35%, 0.5 ± 0.7/mouse, p < 0.01), but not in the wild type males (10%, 0.1 ± 0.3/mouse) as compared to corresponding controls of the same genotype.