Similar to the effects we observed on murine MLL-AF9 AML cells, IL4 stimulation of MA9 cells resulted in suppression of cell proliferation (Supplementary Figure 11a), increased apoptosis via Caspase-3 activation and STAT6 phosphorylation (Figures 7a and b and Supplementary Figure 11b). The gene discussed is CASP3; the disease is acute myeloid leukemia.