VHL and von Hippel-Lindau disease: For purposes of comparison, VHLs for voxel positions with arteriole dominated microvasculature (Fig. 1b, top right) and venule/capillary dominated microvasculature (Fig. 1b, downright) in edema (gray VHL), contralateral normal white matter (cNWM, light green), and contralateral normal gray matter (cNGM, dark green) are depicted in relation to the tumor VHL.