For example, Koyakutty’ group reported that folic-acid-conjugated fluorescent Au25 nanoclusters showed excellent stability over a wide range of pH from 4 to 14 and fluorescence efficiency of ~5.7% at pH 7.4 in phosphate buffer saline (PBS) and effective protection of nanoclusters by serum albumin and outlooked that the bio-friendly nature, near-infrared fluorescence and receptor specific cancer targeting ability of Au clusters would make them an ideal candidate for optical-imaging-based cancer detection16. This evidence concerns the gene ALB and cancer.