Rs13015993 in IGFBP5 and rs7568039 in IGFBP2 might be associated with CAD/MI other than via TSH50 because associations with CAD were suggested by the MR Catalogue (p value 1.73 × 10−4 for rs13015993; 1.40 × 10−4 for rs7568039). The gene discussed is IGFBP2; the disease is coronary artery disorder.