Treatment with SB-431542 (10 μM), JSI-124 (0.2 μM), or SB-431542 (5 μM) + JSI-124 (0.1 μM) inhibited the expression of JAK2, STAT3, survivin and c-myc in lung cancer cells in normal medium and MF-CM, based on RT-PCR measurements (Fig. 5A–D and Supplemental Fig. 5A–D) and by Western Blots (Fig. 5E and F). Here, STAT3 is linked to lung cancer.