PARK7 and Parkinson disease: Various putative functions of DJ-1 in PD have been proposed, including roles as a redox-sensitive chaperone, antioxidant, transcriptional regulator, protease and protein deglycase (Shendelman et al., 2004; Taira et al., 2004; Xu et al., 2005; Chen et al., 2010; Richarme et al., 2015).