ANXA5 and retinal disorder: For example, fluorescein and indocyanine green angiography permits diagnosis of retinal disorders via visualization of retinal and choroidal vasculature abnormalities (108) and, more recently, our group has developed the DARC (detection of apoptotic retinal cell) technology that uses fluorescently labeled annexin A5 to provide a snapshot of the number of dying cells in the retina at a specific time point (109, 110).