In addition to its association with cell cycle progression in our study, enhancer of Zeste homolog 2 (EZH2) – a histone methyltransferase – is potentially tumorigenic by virtue of the fact that it methylates and inactivates tumor suppressor genes and contributes to a state of proliferation and dedifferentiation in tumors and in facilitating their migratory potential [11–16]. This evidence concerns the gene EZH2 and neoplasm.