CSPG4 and melanoma: Besides, 90% of melanoma lesions express the surface protein melanoma-associated-chondroitin-sulfate-proteoglycan (MCSP), also known as chondroitin sulfate proteoglycan 4 (CSPG4) or high molecular weight-melanoma-associated antigen (HMW-MAA) [48], which can be attacked with CARs [49].