Thus, these data show that daily IM doses of up to 20 mg/kg do not cause: i) anemia, neutropenia, lymphopenia or thrombocytopenia suggestive of hematologic toxicity; ii) increases on blood urea nitrogen or creatinine suggestive of renal toxicity; or iii) increases on alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, or bilirubin suggestive of liver toxicity. This evidence concerns the gene GPT and lymphopenia.