KDR and gestational diabetes: In parallel experiments a significant increase (2.2- and 1.8-fold, respectively) in the relative amount of KDR protein (immunocytochemistry; Fig 6C–6F) and tube length (Matrigel assay; Fig 6G and 6F) was found in HUVECs isolated from normal pregnancies exposed (8h) to CM-GDM in comparison to untreated cells.