KLF6 and colorectal cancer: miR-1301 overexpression was observed in prostate cancer, squamous cell carcinomas, and colorectal cancer with liver metastasis.12, 22, 23 Liang et al.11 found that miR-1301 was highly expressed in liver cancer cell lines as well as clinical specimens, and that miR-1301 overexpression promoted cell migration and angiogenesis by targeting the tumor suppressor KLF6-FL.