Core components and upstream regulators such as LATS1/2 and mammalian Ste20‐like kinases 1 and 2 (MST1/2) predominantly function as tumour suppressors, whereas PDZ‐binding Motif (TAZ), Yes‐associated protein (YAP) and (TEA)‐domain family members (TEADs) promote oncogenic events 7, 8, 9. The gene discussed is MST1; the disease is neoplasm.