In the current study, statistical comparison between the 2 groups revealed that seropositive H. pylori status is associated to increasing risk of developing gastric cancer [38, 39] and that H. pylori cagA+ strains are more aggressive than H. pylori cagA- strains, being also linked to stomach adenocarcinoma progression [11, 12]. Here, S100A8 is linked to gastric adenocarcinoma.