AZGP1 and metabolic syndrome: Furthermore, circulating ZAG levels were significantly lower in MetS with overweight/obese (n = 156) and control subjects with overweight/obese (n = 79) than their lean subjects (MetS, n = 99; control, n = 155) (MetS: 31.4 ± 10.1 vs. 40.8 ± 11.9 μg/L; Controls: 35.1 ± 12.0 vs. 51.6 ± 18.9, both P < 0.01) (Fig. 1c).