Comprehensive genomic profiling of primary non-small cell lung carcinoma (NSCLC) has identified mutations of multiple driver genes, especially oncogenes such as AKT1, ALK, EGFR, ERBB2, KRAS, MET, NRAS, BRAF, PIK3CA, RET, ROS1, and others [1, 2]. The gene discussed is RET; the disease is non-small cell lung carcinoma.